Table of Contents
A Letter from
Anne Beattie, Coordinator 8
A Letter from Ralph W. Moss, PhD 9
How to Use This Report 15
Conventional Treatment Modalities 16
Some general principles 18
Classification of breast tumors 20
Staging criteria: the AJCC staging system 22
Hormone receptor and HER-2/neu status 23
Overview of treatment 25
Stage 0 - DCIS and LCIS 25
Axillary lymph node dissection and sentinel node biopsy 30
Stage I breast cancer 31
Stage II breast cancer 34
Timing of breast cancer surgery 35
Ovarian ablation 35
Chemotherapy - An Overview 36
Radiation therapy - an overview 41
Stage III invasive breast cancer 44
Surgery and axillary lymph node dissection for stage III cancer
45
Stage IV and recurrent breast cancer 46
Hormone therapy - tamoxifen 47
Aromatase inhibitors and other hormonal approaches 51
Immunotherapy for breast cancer 54
Programmed cell death and COX 2 inhibitors 55
Targeted treatments and new ideas 56
Prognosis in breast cancer 58
Breast cancer survival rates by stage 58
Recurrence and follow up 59
Breast reconstruction 61
Tumor markers in breast cancer 61
Some markers of diagnosis 62
Serum diagnostic markers for breast cancer 63
Prognostic markers for breast cancer 64
Markers for breast cancer progression and metastasis 64
Markers important for treatment decisions 65
Decision-making tool in breast cancer 67
Dealing with Conventional Treatment 68
Fatigue and cancer 71
Alternative medicine and anemia 73
Blood clotting disorders that accompany cancer 73
Alternative medicine and clotting disorders 74
Natural agents that inhibit platelet aggregation 75
The Treatment of Metastatic Cancer 77
Causes of metastasis 77
Iatrogenic metastases 81
Liver metastases 82
Staging of patients with liver metastases 83
Treatment of liver metastases: surgery 84
Treatment of liver metastases: chemotherapy 85
Treatment of liver metastases: radiation 89
Cryosurgery for liver metastases 91
Image-guided percutaneous tumor ablation 93
Alternative approaches to liver metastases 95
Ascites and abdominal cavity metastases 95
Abdominal cavity metastases 100
Alternative medicine and malignant ascites 102
Lung metastases 103
Treatment of lung metastases 104
Symptoms and complications of lung metastases 106
Brain metastases 107
Treatment of brain metastases 109
Symptomatic relief 109
Brain metastases and alternative medicine 115
Bone metastases 116
Pathology and symptoms of bone metastases 117
Treatment of bone metastases 119
Clinical Trials 121
Phase I trials 129
Phase II trials 132
Phase III trials 133
Questions to ask 134
Choosing a trial 135
Innovative Chemotherapy 136
Chemosensitivity testing 136
Insulin potentiation therapy (IPT) 141
Metronomic chemotherapy 144
Chronotherapy 147
Innovative Radiation Therapy 152
Restricted field techniques 154
Body radiosurgery 158
Modified Fractionation Schemes 161
Extended field therapies 162
Radiosensitizers and radioprotectors 163
Non-Ionizing Forms of Energy 165
Hyperthermia 165
Clinical trials of hyperthermia 169
US Hyperthermia clinics 172
Academic centers using hyperthermia 173
Photodynamic therapy (PDT) 179
Galvanotherapy (EChT) 182
Radiofrequency ablation (RFA) 185
High intensity focused ultrasound (HIFU) 185
Antioxidants and Cancer Treatment 187
Innovative Cancer Clinics 199
CAM Clinics in the US and abroad: making a decision 200
Traveling for treatment: offshore clinics 205
CAM-Friendly Physicians 210
United States and Other English-Speaking Countries 210
US: State-by-State Listing 213
English-Speaking Countries Outside the US 242
Australia 242
Caribbean 243
Canada 243
United Kingdom 244
Philippines 245
Northern European Clinics 246
BioMed Klinik (Dieter Hager, MD, PhD) 247
St. Georg Hospital (Friedrich Douwes, MD) 248
Hufeland Klinik (Wolfgang Woeppel, MD) 251
Herzog Clinic (Alexander Herzog, MD) 252
Humlegaarden (Finn Sk¿tt Andersen, MD) 253
Institute for Cancer Therapy (Thomas Nesselhut, MD) 255
Mexican Cancer Clinics 256
Sanoviv (Myron Wentz, PhD) 260
IPT clinic (Donato Perez Garcia III, MD) 261
The Gerson program (Charlotte Gerson) 261
The Issels program (Ilse Marie Issels) 261
International BioCare (Rodrigo Rodriguez, MD) 262
Oasis of Hope (Francisco Contreras, MD) 262
The San Diego Clinic (Filiberto Munoz, MD) 263
Stella Maris Clinic (Gilberto Alvarez, MD) 263
Santa Monica Hospital (Kurt Donsbach, DC) 263
Biomedical Center (Liz Jonas) 264
New Century Clinic (Hulda R. Clark, PhD) 264
American Metabolics Institute (Geronimo Rubio, MD) 264
Food and Cancer 265
Is organic food dangerous? 271
Proteins to eat in moderation 277
Proteins to avoid 278
Vegetarian and vegan diets 282
Special foods 286
Foods to avoid 287
Special Dietary Programs 290
The Gerson program 290
Macrobiotics 293
The Kelley method 297
Nicholas J. Gonzalez, MD 298
Jack Taylor's Metabolic Assessment Program 302
Ann Wigmore and wheat grass 303
Supplements 305
Preventing side effects of radiation 308
A list of caveats regarding antioxidants 308
Interactions and contraindications 309
Herbs and Botanicals 311
Finding an herbalist 315
A Quick Guide to CAM Treatments 317
Guide to Alternative Approaches 319
Acupuncture 320
Alivizatos 320
AMAS Test 321
Amino acid therapy 322
Anthroposophical medicine 322
Antineoplastons 323
Active specific immunotherapy 325
Active non-specific immunotherapy 326
Active Hexose Correlated Compound (AHCC) 328
Artemisinin 329
Autohemotherapy 330
BCG 330
Beta-carotene 331
Bilwa 332
Bioresonance 332
Biological dentistry 333
Black salves 334
Burdock root 335
Cancell 335
Carnivora 336
CarTCell shark cartilage 337
Cat's Claw 338
Cesium chloride 339
Chaparral 340
Chelation, EDTA 342
Chlorella 342
Cimetidine (Tagamet) 344
Clark method 346
Clover 348
Coffee 349
Coffee enemas 349
Coriolus versicolor (PSK) 352
C-statin 353
Coley's toxins (Waisbren method) 354
Colostrum/Transfer factor 356
Cromolyn 358
Dendritic cell vaccines 359
DHEA 360
DMSO 360
Electrodermal screening 360
Escozul 361
Essiac 362
Fever therapy 363
Flaxseed 363
Galavit 364
Garlic and onions 365
Glutamine 366
Glutathione 369
Goji 370
Graviola 371
Haelan 951 372
Heat shock proteins 373
Homeopathy 373
Hoxsey 376
Hydrazine sulfate 379
Hyperbaric oxygen 379
Immunotherapy 380
Indole-3-carbinol 382
Insulin Potentiation Therapy 383
IP6 (Cell Forte) 383
Issels program 383
Jason Winters tea 384
Jiaogulan 385
Juicing 385
Kirlian photography 386
Kloss formula 386
Laetrile 387
Live cell therapy 388
Maitake 390
Mangosteen 391
Marijuana 393
Melatonin 393
Methylglyoxal 397
MGN3/Biobran 398
Mistletoe 399
Modified citrus pectin 402
Naessens 403
N-acetyl cysteine (NAC) 404
Naltrexone, low-dose (LDN) 405
Newcastle disease virus vaccine 406
NeyTumorin 408
Noni juice 408
Noscapine 409
Oleandrin (Anvirzel, Xenavex) 410
Oxygen therapies 412
Pau d'arco 414
PC SPES 416
PolyMVA 419
pH therapy 420
Red root-burdock formula 422
Reishi 423
Sanum remedies 425
Rath, Matthias 426
Saffron 427
Sea buckthorn 427
Seacure¨ 428
Spirulina 429
Sprouts 430
Sun soup 431
Tangeretin 434
Tea 434
Thermography 438
Tian Xian 438
Tomatoes and lycopene 439
Ultraviolet blood irradiation (UBI) 440
Urea-creatinine 442
Urine therapy 442
Vitamin A 443
Vitamin C 443
Vitamin D 446
Vitamin E 446
Whole body hyperthermia 448
Yu therapy 448
Resources 450